No. 1688, Gaoke East Road, Pudong new district, Shanghai, China.
No. 1688, Gaoke East Road, Pudong new district, Shanghai, China.
We know that many different things affect aging: genetics, diet, exercise, illness, and a host of other factors, all of which contribute to the aging process. A series of remarkable biological research studies since the 1990s have identified genes that can profoundly influence the rate at which cells, and animals, age.
In 2050, 80% of older people will be living in low- and middle-income countries. The pace of population ageing is much faster than in the past. In 2020, the number of people aged 60 years and older outnumbered children younger than 5 years.
Aging, progressive physiological changes in an organism that lead to senescence, or a decline of biological functions and of the organism's ability to adapt to metabolic stress. The aging process takes place over the entire adult life span of any living thing.
You know that aging will likely cause wrinkles and gray hair. But do you know how aging will affect your teeth, heart and sexuality? Find out what changes to expect as you continue aging — and how to promote good health at any age.
Human aging, physiological changes in the human body that lead to senescence, involving declines in biological functions and the ability to adapt to metabolic stress. These physiological developments usually are accompanied by psychological and behavioral changes and social and economic changes.
Aging is a complex result of many biological processes, and many key factors trigger aging, such as DNA damage, telomere dysregulation, mitochondrial dysregulation, NAD + loss, autophagy disorders, and stem cell exhaustion. Here, we summarise the main causes and underlying molecular mechanisms contributing to the aging process.
Several aging mechanisms have been identified, primarily including genomic instability, telomere shortening, and cellular senescence. Aging is a driving factor of various age-related diseases, including neurodegenerative diseases, cardiovascular diseases, cancer, immune system disorders, and musculoskeletal disorders.
Aging is associated with changes in dynamic biological, physiological, environmental, psychological, behavioral, and social processes. Some age-related changes are benign, such as graying hair. Others result in declines in function of the senses and activities of daily life and increased susceptibility to and frequency of disease, frailty, or ...
Aging is a gradual and irreversible pathophysiological process. It presents with declines in tissue and cell functions and significant increases in the risks of various aging-related diseases,...
Aging is a leading cause of disease and disability. This special Research in Context feature explores research into the biology of aging, including how to measure its speed and progression and ways it might be slowed down or even reversed. With advancing age comes an increased risk of disease and disability.
